Skin Pigmentation

Result-driven treatments to eliminate undesired skin spots
All that you should know about Skin Pigmentation & Skin Whitening

Spotty and blotchy skin is a nightmare for all. Skin pigmentation is a very common skin problem in men & women. Let us first understand what is skin pigmentation and what causes it. Our skin has cells called melanocytes which produce a pigment called melanin. Melanin gives the skin its colour. The number of melanocytes present in our skin determines our skin colour. Melanin also protects our skin from the harmful effects of sun radiation.

The sun emits two types of rays i.e. UVA and UVB. When the skin is exposed to the UVB radiation, the upper layer of the skin, called epidermis, gets burnt leading to sunburns. Whereas UVA radiation can penetrate deeper into the skin (dermis) and trigger melanocytes to produce excess melanin leading to pigmentation. Dermis contains blood vessels and nerves and UVA by damaging dermis also leads to premature ageing.

The melanocytes produce more melanin as and when our skin is exposed to more sun. The quanitity of melanin produced varies from one individual to other. This excess melanin is then deposited under the skin, which leads to skin tan, darker patches or pigmentation. Hormonal imbalance usually triggered during pregnancy or by taking birth control pills can be another cause of pigmentation. This condition is termed as melasma. Other reasons of pigmentation include acne and skin concerns like dermatitis, eczema etc.

Cosmetica Skin offers effective treatment of Skin Pigmentation by chemical peels. Acids at stronger concentrations are used to treat the desired area of skin. Trained dermatologists will help you pick a peel which suits your skin type and yields quicker results than ordinary peels. Have any queries about pigmentation? Click to book online appointment with our Dermatologist or email your questions to

Skin brightening

Skin brightening or whitening is the most desirable skin treatment used these days. Unlike earlier times, not just celebrities but even normal people are taking keen intrest in maintaining their skin colour. Due to tanning and sun exposure our skin colour becomes a few shades darker. “ Nowadays it is very common to see brides and aspirant models wanting to brighten their skin tone. Not just them but even people who heavily expose their skin to sun as part of their daily job, seek skin brightening treatments as it is so easily approachable” said Dr. Sanjay Sakarwal, leading dermatologist in Jaipur.

There are many effective techniques used for skin brightening. The most promising and talked about among them is IV Glutathione Therapy. It is all about lightening your skin from the inside, with Glutathione and Vitamin C injected into your bloodstream via a small butterfly needle. IV Therapy allows for these active ingredients to go directly into the bloodstream and hence, are absorbed much more effectively than taken orally.

IV Glutathione Skin Lightening Therapy works best for darker skinned ethnic groups, such as Asian (Filipino, Chinese, Korean, etc), East Indian, African, Hispanic, or simply for anyone with skin darkened from UV rays from being outdoors. IV Glutathione is also regularly used by all men and women who wants to maintain good skin complexion and general health.

Glutathione (GSH) is the body’s most powerful anti-oxidant and detoxifier, made from three amino acids glycine, cysteine, and glutamic acid. Glutathione has other functions in the body as well including elimination of free radicals and toxic substances, skin rejuvenation, tissue repair, regeneration of liver cells from alcohol damage and fatty food intake and improving immunity.

Glutathione is effective in lightening the skin because it reduces the production of melanin in melanocyte cells (melanin is the molecule responsible for pigmentation).

Vitamin C is also injected to help the body clear reactive oxygen species (ROS). Vitamin C neutralizes and eliminates these harmful free radicals, hence, reduces the effects of aging. It also helps increase production of collagen to help smooth out fine lines and wrinkles.

The dose of Glutathione injectible is delivered in a cylce of one per week.The number of cycles needed is dependant on how dark your skin is, how many shades you plan on lightening, how fast you want to achieve results and ultimately, how your body responds to the treatment.

IV Glutathione is very suitable for anyone looking to lighten their skin, improve their complexion, treat darkened skin due to UV sun exposure, or clear skin blemishes and melasma.

This treatment is contra-indicated for pregnant or breastfeeding women, patients with cancer, renal failure, cardiovascular disease, G6PD, high blood pressure, diabetes, liver or kidney diseases. If you are on any medication or have any other chronic conditions, always consult your dermatologist first.

Latest: Vitiligo

There is no known cause of vitiligo, a disease in which the immune system attacks pigment cells in the body. Vitiligo may range from mild to severe and can be found anywhere on the body, although it typically affects exposed areas, such as the face and hands. While vitiligo is not evident at birth, about half of vitiligo patients contract the disease before age 20. Approximately 50 million people -- one percent of the worldwide population -- are affected by vitiligo, including musical artist Michael Jackson, actor John Hamm, model Winnie Harlow and comedian Steve Martin. Vitiligo affects all ethnic groups equally, but is more evident in ethnic minorities with darker skin. No FDA-approved re-pigmenting treatments for vitiligo currently exist.

"Unfortunately, there is often a social stigma associated with vitiligo, and it can take a significant psychosocial toll on patients," said Dr. Rosmarin. "Current treatments such as phototherapy, topical corticosteroids, and calcineurin inhibitors have limited efficacy, and phototherapy treatment can be a burden for patients to have to use a light box two or three times per week." <

Source: Tufts Medical Center. "Topical cream shows promise in treatment of skin pigmentation disease, vitiligo." ScienceDaily. ScienceDaily, 17 June 2019. .

The two-year study, the largest randomized controlled vitiligo study ever conducted, enrolled 157 patients at 30 sites across the United States. Participants received daily or twice daily topical application of either ruxolitinib or placebo to the area of skin affected by vitiligo. About half of the highest dose of ruxolitinib patients saw a statistically significant improvement of near 50 percent in their facial vitiligo, compared to three percent who saw this level of improvement in the placebo group. Side effects of topical application of ruxolitinib were mild and included redness and irritation at the application site and mild acne.

"Topical ruxolitinib has the potential to change the way vitiligo is treated. Not only is it effective at repigmenting the skin, but it has an excellent safety profile," said Dr. Rosmarin. "We also are optimistic that many vitiligo patients may see an even better response with continuous ruxolitinib usage over an extended period of time, combined with phototherapy and sunlight exposure. Our hope is that this treatment ultimately will be a game-changer for the millions of people worldwide affected by vitiligo."